Plant flavonoid found to reduce inflammatory response in the brain: luteolin

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Plant flavonoid found to reduce inflammatory response in the brain: luteolin

June 29, 2014 by larryhbern

This is quite interesting. It does not fully account for effects we also know, matrix metalloproteases in particular, but also it does not address hyperhomocysteinemia and lean body mass in the elderly cohort.

Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign



		IMAGE:Animal sciences professor Rodney Johnson, and graduate student Saebyeol Jang found that a plant flavonoid, luteolin, inhibited a key pathway in the inflammatory response of microglia. Click here for more information.

Researchers at the University of Illinois report this week that a plant compound found in abundance in celery and green peppers can disrupt a key component of the inflammatory response in the brain. The findings have implications for research on aging and diseases such as Alzheimer’s and multiple sclerosis.

The study appears this week in Proceedings of the National Academy of Sciences.

Inflammation can be a blessing or a blight. It is a critical part of the body’s immune response that in normal circumstances reduces injury and promotes healing. When it goes awry, however, the inflammatory response can lead to serious physical and mental problems.

Inflammation plays a…

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