Leaders in Pharmaceutical Business Intelligence (LPBI) Group

TODAY – 11:45 am – 1:30 pm Awards Luncheon – MassBio Annual Meeting 2014, Royal Sonesta Hotel, Cambridge, MA

Reporter: Aviva Lev-Ari, PhD, RN

Conference Coverage for Scientific and Social Media: Aviva Lev-Ari, PhD, RN   11:45 am – 1:30 pm Awards Luncheon 11:45 am – 12:00 pm Awards Luncheon: Lunch is served 12:00 pm – 12:20 pm Leading Impact Award 12:20 pm – 12:45pm 2013 Joshua Boger Innovative School of the Year Award 12:45 pm – 1:30 pm Henri A. Termeer Innovative Leadership Award

AWARDS given for education by Takeda

• Assabet Valley Regional Technical High School – Monica Haize, Teacher of Biology, Inspiration of students, MassBio & Takeda, her genetics elective cultures bacteria, freshman curriculum: high school student get hands on in the Labs, motivations by trips and workshop. BioTeach Project symbiotic biology, Marine Biology, PCR, applied. 18 vocational training on the weekend. STEP, stat classes, using biotech, bacteria transformation  project. The award will go to support materials in the labs. Sophomore student will present now: STEM is his life:
• Biogen idec CEO, George Scangos, UMass Alumnus, raised in Lynn, MA – is awarded Henri A. Termeer (ex- Genzyme) Innovative Leadership Award, joined Biogen from Atatexis, prior Academics at John Hopkins Universiry. MA is the Leader in Biotech, 120 Universities get the highest NIH grants,

George Scangos: of 11 Largest Pharma, 10 have Labs in MA.Tax Incentives to Biotech to be translated to therapies. MassBio and Bioger were the first in the State. CAMBRIDGE, MA, Biogen – 26 years ago started in Cambridge, 1/2 of products in Cambridge and HQS in Cambridge. Closest to Labs at Universities: ALS disease – missfolding of proteins, Proteomics expertise, coalition of Academics, Duke, sequence 1,000 then 5,000, 20-30,000 without ALS -Collaboration, Harvard, Columbia, Rockefeller – Lawyers worked on IP matters to make it work. Areas in Genomics, Translational medicine will bring therapies to patients. Collaborations on complex diseases, Parkinson, Gene Editing, ISIS, Consortium on Hematology, Harvard collaboration on pathways of proteins. Postdocs fellowship at Biogen with Universities. Government funding – cut backs, industries are stepping up. Negative Understanding biology of Diseases:

• MS – disease drug development – SLOW and change the nature by reverse. Modify therapies, drug that repair – phase ii drug, risky project. Point estimate – does the drug help??? How fast walk, for how long – REAL TIME MEASUREMENT no more point measurement
• Alzheimer’s’ Disease – society impact cost of caring, Biogen has the responsibility
• Parkinson
• ALS – 3 years from Dx to death
• Hemophilia

Government initiative – MP6 – accelerate CMS- propose cuts Part D – reversed, Reimbursement for Treatment, One letter from FDA – affected investors and the stock market. Economic analysis take time, Reimbursement for cost of innovation should come by government, continue support for innovation. Policy makers in MA had strong leadership and support Biotech Industry in MA. Have to insure balance IP, Regulatory 12 years for Biologics, Advanced Medicine, NIH, CDC, FDA, support initiatives, regulation of drugs, Market based for Reimbursement, great benefit to Patient. Corporate Tax must be updated. Corporate Tax is the highest in the US, must go down.

• MS – 9 approved drugs
• HIV – cocktail drugs
• social contracts with patients to stay in place
• DATA – How to use it in R&D, negotiate a price with Insurance for Reimbursement, it will be based on collaborative DBs for best interest of patients.

Most exciting time in BIOTECH, more advances will emerge: Economics, Medicine, together, challenging: Policies: Reimbursement,. Award named after Termeer – never stop trying to do best for life of Patients.

MassBio Impact Award Presentation introduced by Shire for Governor Deval L. Patrick who championed of Life Science Initiative in MA – becoming the GLOBAL leader in BioTech. 

• Thousands of jobs created in Biotech: Gov’t and Industry,
• Grants and
• Tax initiative
• Investing through in R&D, infrastructure, Worcster, UMass Center, Springfield center, Joslin new building in Longwood Hospital area
• Workforce development : High School
• Life sciences inclusive
• CNS – Priority Neuroscience Consortium : collaboration Merck Sorono, Biogen idec,
• Recognition of group of sectors in the economy of the MA State: Academia and Industry and Government