Unraveling Retrograde Signaling Pathways
Reporter: Larry H. Bernstein, MD, FCAP
Image Source: Created by Noam Steiner Tomer 8/10/2020
Unraveling retrograde signaling pathways: finding candidate signaling molecules via metabolomics and systems biology driven approaches
C Caldana, AR Fernie, L Willmitzer and D Steinhauser
Front. Plant Sci. 2012; 3:267. http://dx.doi.org/10.3389/fpls.2012.00267
signals can be generated within organelles, such as chloroplasts and mitochondria,
- modulating the nuclear gene expression in a process called
- retrograde signaling.
Recently, integrative genomics approaches, in which correlation analysis has been applied on transcript and metabolite profiling data
of Arabidopsis thaliana, revealed the identification of metabolites which are
- putatively acting as mediators of nuclear gene expression.
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