Reporter: Aviva Lev-Ari, PhD,RN
Functional Genomics Screening Strategies: Part One
Utilizing RNA Interference (RNAi) Screens
to Explore Drug Targets and Cellular Pathways
Boston, MA | September 24-25, 2013
Dr. Scott Martin, Team Leader for RNAi Screening at NIH’s Chemical Genomics Center, to Present “Swimming in the Deep End – Sources Leading to a False Sense of Security in RNAi Screen Data” at Functional Genomics Screening Strategies Conference
There has been a growing skepticism surrounding RNAi data and the validity of hits arising from largescale RNAi screens. Much of this comes from a lack of agreement between screens conducted in similar biological systems and difficulty in validating published screen hits. In light of these realities, we must rethink some widely held beliefs about screening and validation strategies. These issues and relevant data will be discussed.
Functional Genomics Screening Strategies: Part Two
Exploring Novel Screening Platforms and Cellular
Models for Next-Generation Screens
Boston, MA | September 25-26, 2013
The second half of Functional Genomics Screening Strategies will explore the use of chemical genomics screens, microRNA (miRNA) and long non-coding RNA (lncRNA) screens and the transition into advanced cellular models such as, 3D cell cultures, co-cultures and stem cells that will launch the next generation of functional screens. Screening experts from pharma/biotech as well as from academic and government labs will share their experiences leveraging the utility of such diverse screening platforms and models for a wide range of applications.